Open Books

Published Work

The Fruits of Our Labor

 
  1. Abbasian, M.; Langlois, A.; Gibon, J*. Sexual Dimorphism in Balance and Coordination in the p75NTR exonIII Knock-Out Mice. Frontiers in Behavioral Neuroscience Jan 2022. 

  2. de León, A.;  Gibon, J.; Barker, P.A., NGF- and BDNF-dependent DRG sensory neurons deploy distinct degenerative signaling mechanisms. eNeuro 2020.

  3. Johnstone, A. D.;  de Leon, A.;  Unsain, N.;  Gibon, J.; Barker, P. A., Developmental Axon Degeneration Requires TRPV1-Dependent Ca(2+) Influx. eNeuro 2019, 6 (1). 

  4. Glasgow, S. D.;  Labrecque, S.;  Beamish, I. V.;  Aufmkolk, S.;  Gibon, J.;  Han, D.;  Harris, S. N.;  Dufresne, P.;  Wiseman, P. W.;  McKinney, R. A.;  Seguela, P.;  De Koninck, P.;  Ruthazer, E. S.; Kennedy, T. E., Activity-Dependent Netrin-1 Secretion Drives Synaptic Insertion of GluA1-Containing AMPA Receptors in the Hippocampus. Cell Rep 2018, 25 (1), 168-182.e6. 

  5. Johnstone, A. D.;  Hallett, R. M.;  de Leon, A.;  Carturan, B.;  Gibon, J.; Barker, P. A., A novel method for quantifying axon degeneration. PLoS One 2018, 13 (7), e0199570. 

  6. Thomas, R. A.;  Gibon, J.;  Chen, C. X. Q.;  Chierzi, S.;  Soubannier, V. G.;  Baulac, S.;  Seguela, P.;  Murai, K.; Barker, P. A., The Nogo Receptor Ligand LGI1 Regulates Synapse Number and Synaptic Activity in Hippocampal and Cortical Neurons. eNeuro 2018, 5 (4). 

  7. Gibon, J.*; Barker, P. A., Neurotrophins and Proneurotrophins. Neuroscientist 2017. 

  8. Gaub, P.;  de Leon, A.;  Gibon, J.;  Soubannier, V.;  Dorval, G.;  Seguela, P.; Barker, P. A., HBpF-proBDNF: A New Tool for the Analysis of Pro-Brain Derived Neurotrophic Factor Receptor Signaling and Cell Biology. PLoS One 2016, 11 (3), e0150601. 

  9. Gibon, J.;  Barker, P. A.; Seguela, P., Opposing presynaptic roles of BDNF and ProBDNF in the regulation of persistent activity in the entorhinal cortex. Mol Brain 2016, 9 (1), 23. 

  10. Gibon, J.;  Kang, M. S.;  Aliaga, A.;  Sharif, B.;  Rosa-Neto, P.;  Seguela, P.;  Barker, P. A.; Kostikov, A., Towards the PET radiotracer for p75 neurotrophin receptor: [(11)C]LM11A-24 shows biological activity in vitro, but unfavorable ex vivo and in vivo profile. Bioorg Med Chem 2016, 24 (19), 4759-4765 

  11. Gibon, J.;  Unsain, N.;  Gamache, K.;  Thomas, R. A.;  De Leon, A.;  Johnstone, A.;  Nader, K.;  Seguela, P.; Barker, P. A., The X-linked inhibitor of apoptosis regulates long-term depression and learning rate. Faseb j 2016. 

  12. Gibon, J.;  Buckley, S. M.;  Unsain, N.;  Kaartinen, V.;  Seguela, P.; Barker, P. A., proBDNF and p75NTR Control Excitability and Persistent Firing of Cortical Pyramidal Neurons. J Neurosci 2015, 35 (26), 9741-53. 

  13. Gibon, J.;  Deloulme, J. C.;  Chevallier, T.;  Ladeveze, E.;  Abrous, D. N.; Bouron, A., The antidepressant hyperforin increases the phosphorylation of CREB and the expression of TrkB in a tissue-specific manner. Int J Neuropsychopharmacol 2013, 16 (1), 189-98. 

  14. Bohic, S.;  Ghersi-Egea, J. F.;  Gibon, J.;  Paoletti, P.;  Arnaud, J.;  Hunot, S.;  Boom, A.; Bouron, A., [Biological roles of trace elements in the brain with special focus on Zn and Fe]. Rev Neurol (Paris) 2011, 167 (4), 269-79. 

  15. Gibon, J.;  Richaud, P.; Bouron, A., Hyperforin changes the zinc-storage capacities of brain cells. Neuropharmacology 2011, 61 (8), 1321-6. 

  16. Gibon, J.;  Tu, P.;  Bohic, S.;  Richaud, P.;  Arnaud, J.;  Zhu, M.;  Boulay, G.; Bouron, A., The over-expression of TRPC6 channels in HEK-293 cells favours the intracellular accumulation of zinc. Biochim Biophys Acta 2011, 1808 (12), 2807-18. 

  17. Gibon, J.;  Tu, P.; Bouron, A., Store-depletion and hyperforin activate distinct types of Ca(2+)-conducting channels in cortical neurons. Cell Calcium 2010, 47 (6), 538-43. 

  18. Gibon, J.;  Tu, P.;  Frazzini, V.;  Sensi, S. L.; Bouron, A., The thiol-modifying agent N-ethylmaleimide elevates the cytosolic concentration of free Zn(2+) but not of Ca(2+) in murine cortical neurons. Cell Calcium 2010, 48 (1), 37-43. 

  19. Tu, P.;  Gibon, J.; Bouron, A., The TRPC6 channel activator hyperforin induces the release of zinc and calcium from mitochondria. J Neurochem 2010, 112 (1), 204-13. 

  20. Cortes, M. A.;  Gibon, J.;  Chanteloup, N. K.;  Moulin-Schouleur, M.;  Gilot, P.; Germon, P., Inactivation of ibeA and ibeT results in decreased expression of type 1 fimbriae in extraintestinal pathogenic Escherichia coli strain BEN2908. Infect Immun 2008, 76 (9), 4129-36. 

Publications-non refereed papers-

  1. Glasgow, SD.; Wong, EW.; Beamish, IV.; Lancon, K.; .; Seguela, P.; Ruthazer, ES.; and Kennedy, TE. Acetylcholine synergizes with netrin-1 to drive persistent firing in the entorhinal cortex. BioRxiv. 2020

  2. Tabatabaee MS.; Edemann S.; Menard F.; Optical Control of Ca2+-Mediated Morphological Response in Glial Cells with Visible Light Using a Photocaged Kainoid. ChemRxiv 2020

Abstracts, poster, and oral presentations

  1. Taryn E. Murray, Tyler J. Wenzel, Svetlana Simtchouk , Julien Gibon , Andis Klegeris. (2021)   

  2. Extracellular cardiolipin regulates select immune functions of astrocytes in a toll-like receptor (TLR)4-dependent manner 2021 Alzheimer’s Association International Conference. 2021

  3. Julien Gibon. (2019), Regulation of neuronal persistent firing by neurotrophins in the context of              short-term memory. Biology Seminar Series, UBCO, invited speaker.

  4.  Julien Gibon (2019), Deciphering physiological and pathological signaling pathway of axonal degeneration. Western Canada Biophysics Workshop, UBCO, Invited speaker.

  5. Aaron D. Johnstone, Andrés de Léon, Nicolás Unsain, Julien Gibon, and Philip A. Barker. (2019)                 Developmental axon degeneration requires TRPV1-dependent calcium influx. Gordon Research              conference, neurotrophic factors, Newport, USA

  6. Andrés de León, Julien Gibon, Philip Barker. (2018). Investigation of the role of APP in   developmental axonal pruning. Canadian association for neuroscience, Vancouver, Canada.

  7. Bradley Kievit, Aaron Johnstone, Julien Gibon, Philip Barker. (2018). Reactive oxygen species and            calcium rise through TRPV1 mediate Wallarain Degeneration in injured sensory axons. Biology            Graduate symposium 2018, Kelowna, Canada.

  8. Andres de Leon, Aaron Johnstone, Julien Gibon, Philip Barker. (2019). Developmental apoptosis              of BDNFdependent sensory neurons. Gordon Research Conference, neurotrophic factors,               Newport, USA.

  9. Julien Gibon, Andres De Leon, Min Su Kang, Pierre-Luc Rochon, Arturo Aliaga, Behrang Sharif,   Pedro Rosa -Neto, Philippe Séguéla, Alexey Kostikov, Philip A. Barker (2017) Investigation of             p75NTR small molecule ligands suitable for Positron Emission Tomography Gordon Research             Conference, Neurotrophic factors, Newport, RI, USA.

  10. Julien Gibon(2016) Persistent firing of pyramidal neurons is modulated by BDNF and proBDNF.                 Invited speaker, Nerve Growth Factor meeting, Pacific Grove, CA, USA.

  11. Julien Gibon, Nicolas Unsain, Karine Gamache, Rhalena Thomas, Andres De Leon, Aaron              Johnstone, Philippe Séguéla, Karim Nader, Philip A. Barker (2015). XIAP Regulates LTD-        Dependent Learning in Mice. Society for neuroscience 2015, Chicago, IL, USA.

  12. Rhalena Thomas, Julien Gibon, Carol X.Q Chen, Sabrina Chierzi, Andres Deleon, Keith K. Murai,                 Stephanie Baulac and Philip A. Barker (2015) LGI1 regulates central synapse number through an      NgR1-RhoA signaling pathway. Gordon Research Conference, Neurotrophic factors, Newport, RI,           USA.

  13. Julien Gibon, Philip A. Barker and Philippe Séguéla (2015).BDNF and proBDNF exert opposing     effects on neurotransmitter release and persistent activity in the cortex. Gordon Research               Conference, Neurotrophic factors, Newport, RI, USA.

  14. Stephen D Glasgow, Ian V Beamish, Julien Gibon, Fiorella Guido, R. Anne McKinney, Philippe    Séguéla, Edward S Ruthazer, Timothy E Kennedy (2015) Synaptic function of netrin-1. 4th Annual   Neuroengineering Training Program Workshop, Montreal, Canada.

  15. Julien Gibon, Nicolas Unsain, Shannon Buckley, Vesa Kaartinen, Philip A. Barker and Philippe     Séguéla (2014) BDNF and proBDNF regulate persistent activity in the entorhinal cortex.  Society               for neuroscience 2014, Washington, DC, USA.

  16. Julien Gibon, Nicolas Unsain, Shannon Buckley, Vesa Kaartinen, Philip A. Barker and Philippe     Séguéla (2014)  ProBDNF and p75NTR regulate excitability and firing of pyramidal neurons. 8th Canadian Association for Neuroscience, Montréal, Canada.

  17. Julien Gibon, Shannon Buckley, Nicolas Unsain, Vesa Kaartinen, Philippe Séguéla and Philip A.   Barker (2013) proBDNF and its receptor p75NTR negatively regulate persistent activity in the entorhinal cortex. Society for neuroscience 2013, San Diego, CA, USA.

  18. Julien Gibon, Shannon Buckley, Nicolas Unsain, Philippe Séguéla and Philip A. Barker (2013) p75                 neurotrophin receptor (p75NTR) negatively regulates persistent firing of pyramidal neurons in the entorhinal cortex. Gordon Research Conference, Neurotrophic factors, Newport, RI, USA.

  19. Julien Gibon, Philip Barker and Philippe Séguéla (2012) BDNF activates p75NTR to facilitate          persistent activity of pyramidal cells in the entorhinal cortex. Society for neuroscience 2012, New Orleans, LA, USA.

  20. Julien Gibon, oral presentation (2012), BDNF facilitates persistent activity in pyramidal neurons                of entorhinal cortex via the p75NTR. Integrated program in neuroscience of McGill University,        Montreal, Canada. 

  21. Julien Gibon, Peng Tu, Sylvain Bohic, Pierre Richaud, Josiane Arnaud, Mike Zhu, Guylain Boulay                         and Alexandre Bouron (2011) TRPC6 channels: an unsuspected zinc entry pathway in cortical               neurons ? 10eme colloque de la société des neurosciences Marseille, France.

  22. Julien Gibon, oral presentation (2009) Biological roles of trace elements in the brain with special               focus on Zn and Fe. Colloque IMBG, Grenoble, France.

  23. Julien Gibon, Peng Tu, Pierre Richaud, Josiane Arnaud, Guylain Boulay and Alexandre Bouron   (2009) TRPC6 Form Zinc-Conducting Channels. 20th Colloque des canaux ioniques, Giens,    France.